Johnny Galecki – Then
Johnny Galecki played the role of Leonard Hofstadter, a brilliant but socially awkward physicist, on the show. Leonard is one of the main characters on the show, and his on-again, off-again relationship with neighbor and friend Penny is a major plot line throughout the series. Galecki’s portrayal of Leonard was praised for its nuance and depth, and he brought a sense of vulnerability to the character that made him relatable and endearing to audiences.

Johnny Galecki Then
Johnny Galecki – Now
Since the conclusion of The Big Bang Theory in 2019, Johnny Galecki has continued to stay busy with his acting career. In 2020, he starred in the thriller film The Cleanse alongside Anna Friel and Anjelica Huston. He also returned to television in the HBO Max series The Flight Attendant as a guest star, working alongside Kaley Cuoco once again. Additionally, Galecki has been working behind the scenes as an executive producer on several television shows, including Living Biblically and The Squad. Outside of acting, he is also an avid farmer and owns a large ranch in California where he grows crops and raises animals. While it’s uncertain what the future holds for Galecki, it’s clear that he has continued to pursue his passions and remain active in the entertainment industry.

Johnny Galecki Now
Jim Parsons – Then
Jim Parsons portrayed the character of Sheldon Cooper. Sheldon is a genius theoretical physicist with a quirky personality and many eccentricities, including a strict adherence to routines and rituals. Parsons’ portrayal of Sheldon was praised for its authenticity and nuance, and he won several Emmy Awards for his performance on the show. His chemistry with his co-stars, particularly Mayim Bialik, who played his wife Amy Farrah Fowler, was a highlight of the series. Parsons’ portrayal of Sheldon helped to make The Big Bang Theory one of the most beloved sitcoms of all time, and his character has become a pop culture icon.

Jim Parsons Then
Jim Parsons – Now
Jim Parsons has remained active in the entertainment industry. In 2020, he starred in the Netflix limited series Hollywood, which was created by Ryan Murphy. He also served as an executive producer on the show. In addition to his work in front of the camera, Parsons has continued to work in theater. He appeared on Broadway in the revival of “The Boys in the Band” in 2018, and served as a producer on the production. Parsons is also an advocate for LGBTQ+ rights and has been involved in several philanthropic initiatives, including The Trevor Project and The LGBT Community Center in New York City.

Jim Parsons Now
Sara Gilbert – Then
Sara Gilbert played the character of Leslie Winkle, a physicist and occasional love interest of Leonard Hofstadter, on the show. Sara Gilbert is also known for her role as Darlene Conner in the TV series Roseanne. Leslie Winkle was a recurring character throughout the series and appeared in several episodes from season one to season three. Gilbert’s portrayal of Leslie Winkle was well-received by audiences and critics alike, and her character’s witty banter with Sheldon and Leonard was a highlight of the show.

Sara Gilbert Then
Sara Gilbert – Now
Gilbert is a talented actress and producer who has received critical acclaim for her performances. In addition to her work in television, Gilbert is also an advocate for LGBT rights and an active member of various social causes. In addition to her acting work, Sara Gilbert is also a co-creator and co-host of the daytime talk show The Talk. She has received several accolades for her performances, including a Primetime Emmy Award nomination for her role in The Big Bang Theory.

Sara Gilbert Now
Mayim Bialik – Then
Mayim Bialik is an American actress and neuroscientist who played the role of Dr. Amy Farrah Fowler. Bialik joined the show in season three and quickly became a fan favorite for her portrayal of Amy, a brilliant neuroscientist and love interest of Sheldon Cooper. Bialik’s performance as Amy was praised for its depth, humor, and emotional range, earning her multiple award nominations, including four Primetime Emmy nominations. Prior to her role on the show, Bialik was best known for her role as Blossom Russo on the TV series Blossom.

Mayim Bialik Then
Mayim Bialik – Now
In addition to her acting career, Bialik is a passionate advocate for science education and women’s health, and has authored several books on parenting and Judaism. She also worked as the host of Jeopardy! National College Championship. Additionally, Bialik served as a guest host for several weeks of the main Jeopardy! series during the show’s search for a permanent replacement host following the passing of longtime host Alex Trebek. Bialik’s guest hosting stint received positive reviews, and she was praised for her intelligence, poise, and warmth on the show, which led her to becoming one of two alternating hosts, switching off with Ken Jennings.

Mayim Bialik Now
Simon Helberg – Then
Simon Helberg is an American actor and comedian who played the role of Howard Wolowitz on the hit TV show. Howard is an aerospace engineer who is known for his quirky personality and love of science fiction. Helberg’s portrayal of Howard was a fan favorite, and his comedic timing and physical humor added to the show’s overall humor.

Simon Helberg Then
Simon Helberg – Now
In addition to his work on The Big Bang Theory, Helberg has also appeared in films such as A Serious Man and Florence Foster Jenkins. He has been nominated for several awards for his work on the show, including five Primetime Emmy Awards for Outstanding Supporting Actor in a Comedy Series. Additionally, Helberg co-wrote and directed the 2021 comedy-drama film We’ll Never Have Paris, which was loosely based on his own romantic experiences. He has also made guest appearances on various TV shows, including Kidding and Drunk History. Outside of his acting work, Helberg is also a talented pianist and has performed in various concerts and events.

Simon Helberg Now
Laura Spencer – Then
Laura Spencer is an American actress who played the role of Emily Sweeney. Emily is a dermatologist who is briefly involved with Raj Koothrappali. Spencer’s portrayal of Emily was well-received by audiences and critics, and her character added an interesting dynamic to the show’s group of friends.

Laura Spencer – Then
Laura Spencer – Now
In addition to her work on The Big Bang Theory, Spencer has appeared in several TV shows and films, including Bones, Sleepy Hollow, and The Lizzie Bennet Diaries. She has also worked as a voice actress and has provided her voice to various animated series and video games.

Laura Spencer Now
Kunal Nayyar – Then
Kunal Nayyar is an Indian-British actor who gained widespread recognition for his role as Raj Koothrappali. Raj is a shy astrophysicist who struggles to communicate with women, which often leads to humorous situations. Nayyar’s portrayal of Raj was beloved by fans for its comedic timing and heartfelt moments, and he became one of the show’s most popular characters. Throughout the series’ 12 seasons, Nayyar’s performance earned him critical acclaim and several award nominations, cementing his status as one of the show’s breakout stars.

Kunal Nayyar Then
Kunal Nayyar – Now
Since the show ended, Nayyar has been involved in several projects. In 2020, he appeared in the drama film Trolls World Tour, providing the voice of the character Guy Diamond. He also starred in the Netflix series Criminal: UK, in which he played the role of Sandeep Singh. Additionally, Nayyar has been working on his own projects, including a memoir titled Yes, My Accent Is Real, which was published in 2015, and a children’s book titled The Ice Monster, which was released in 2018. He has also been involved in philanthropic efforts and has served as an ambassador for several charitable organizations.

Kunal Nayyar Now
Kevin Sussman – Then
Kevin Sussman is an American actor best known for his role as Stuart Bloom. Stuart is the owner of the comic book store that the main characters, including Sheldon and Leonard, often visit. Sussman’s portrayal of Stuart brought a unique brand of humor to the show, with his awkward and self-deprecating personality often serving as a foil for the more confident and socially adept characters. Despite his nerdy exterior, Stuart also displayed a kind and empathetic nature, earning him a place as a recurring character throughout the series. Sussman’s performance was widely praised, and he became a fan favorite over the course of the show’s twelve-season run.

Kevin Sussman Then
Kevin Sussman – Now
In addition to his work on Big Bang Theory, Sussman also with with his Big Bang co-star John Ross Bowie to create two other shows called The Ever After Part and The Second Coming of Rob. Sussman has also worked on other projects including The Dropout, Call Me Kat, Better Call Saul, and Lessons In Chemistry.

Kevin Sussman Now
Alessandra Torresani – Then
In 2016, Alessandra Torresani had a six-episode arc on The Big Bang Theory, in which she portrayed Claire, an aspiring screenwriter who is working as a bartender. She is a writer for kids’ sci-fi series and the crew meet her while they’re at a comic book shop. Claire is looking to work with Raj on the science aspects of the script.

Alessandra Torresani – Then
Alessandra Torresani – Now
Following her work as Claire on The Big Bang Theory, Torresani also appeared in TV shows Lucifer and Batwoman. In addition to her acting work, she also hosts a podcast called EmotionAL Support with Alessandra Torresani, which focuses on mental health. Torresani has openly discussed living with bipolar disorder.

Alessandra Torresani Now
Aarti Mann – Then
Aarti Mann portrays Priya Koothrappali, Raj’s sister. After she graduated from the University of Cambridge, Priya became a top attorney for a famous Indian car company. She ends up dating Leonard for much of season 4 and 5 while she moves to Los Angeles, but the two part ways once she moves to India and is not faithful to Leonard.

Aarti Mann Then
Aarti Mann – Now
After appearing on The Big Bang Theory, Mann has appeared in several guest spots on TV shows including Futurestates, Leverage, Suits, Wendell & Vinnie, Scandal, NCIS: New Orleans, Grey’s Anatomy, Never Have I Ever, All Rise, and The Good Doctor. She landed a main role in TV show The Recuit, on which she plays the role of Violet.

Aarti Mann Now
Sara Rue – Then
Sara Rue had a three episode appearance on The Big Bang Theory in 2008, where she played Dr. Stephanie Barnett, a physician who was Leonard’s girlfriend for a short while. Prior to her role on the show, she appeared in many other films and TV shows including Pearl Harbor, The Ring, Idiocracy, Two and a Half Men, MadTV, Will & Grace, and ER.

Sara Rue Then
Sara Rue – Now
After appearing as a guest star on Big Bang, Rue continued her acting career, landing main roles in shows like Eastwick, Malibu Country, Impastor, and B Positive. She is also known for her roles on Popular, Less than Perfect, Rules of Engagement, hosting Shredding for the Wedding, and A Series of Unfortunate Events.

Sara Rue Now
Margo Harshman – Then
Margo Harshman appears in season 6 of the show playing the role of Alex Jensen, a graduate assistant working with Sheldon. She is hired to review his work to find any potential for Nobel Prize winning research. She becomes interested in Leonard, who is still dating Penny, which makes him feel quite good about himself but causes Penny to feel jealous. Sheldon gets upset and attempts to give her a talking to, which of course ends up going hilariously wrong.

Margo Harshman Then
Margo Harshman – Now
Following her role on Big Bang Theory, Harshman has appeared in TV shows like Betas, Bones, CSI: Crime Scene Investigation, NCIS, and most recently How I Met Your Father. She has also previously starred in shows like Everwood, Grey’s Anatomy, Journeyman, 90210, Boston Legal, Modern Family, and House.

Margo Harshman Now
Brian Patrick Wade – Then
Brian Patrick Wade had a small appearance in three episodes of Big Bang Theory, on which he portrayed Kurt, Penny’s brawny former love interest that clearly intimidates Leonard. Before his role on Big Bang, Wade also starred in CSI: Miami, Sabrina the Teenage Witch, NCIS, Las Vegas, Surface, Twenty Good Years, Mafiosa, Two and a Half Men, Help Me Help You, ‘Til Death, and The Closer.

Brian Patrick Wade Then
Brian Patrick Wade – Now
Following his appearance on the show, Wade continued acting in TV shows including Generation Kill, The Game, NCIS, Alligator Point, NCIS: Los Angeles, Best Friends Forever, The Glades, Arrested Development, Teen Wolf, Hello Ladies, The Mentalist, Agents of S.H.I.E.L.D, and A Loud House Christmas.

Brian Patrick Wade Now
Valerie Azlynn – Then
Valerie Azlynn is an American actress who appeared in one episode, playing the role of Alicia, a woman who Leonard Hofstadter meets through an online dating site. Alicia is portrayed as an attractive but slightly ditzy woman who Leonard initially believes might be his perfect match. However, as the date progresses, Leonard becomes increasingly frustrated by Alicia’s lack of intellectual curiosity and her preoccupation with her ex-boyfriend. While Valerie Azlynn’s appearance on the show was brief, her performance as Alicia added an element of humor and served to highlight Leonard’s struggle to find a meaningful relationship.

Valerie Azlynn Then
Valerie Azlynn – Now
Valerie Azlynn is still actively working in the entertainment industry. She has continued to act in both television and film projects since her appearance on The Big Bang Theory. Some of her notable roles include appearances in shows such as Sullivan & Son, Hot in Cleveland, and Castle, as well as in films like Tropic Thunder and Poseidon. In addition to her acting work, Azlynn has also been involved in various charitable causes, including the organization Smile Train, which provides cleft lip and palate surgeries for children in need.

“The Watch” Los Angeles Premiere Arrivals
Brooke D’Orsay – Then
In the show’s tenth season, Beth D’Orsay portrayed the character of Paige, the wife of Bert Kibbler, a geologist friend of the show’s main characters. Paige is depicted as an attractive and outgoing woman who is often oblivious to the awkwardness of the show’s main characters. She first appears in the episode “The Geology Elevation” and later in “The Gyroscopic Collapse”. D’Orsay’s portrayal of Paige brought a fresh energy to the show and added an interesting dynamic to Bert’s character.

Brooke D’Orsay Then
Brooke D’Orsay – Now
In addition to her appearance on The Big Bang Theory, Brooke D’Orsay has also had notable roles in other television shows such as Royal Pains and Two and a Half Men. In 2018, she starred in the Hallmark Channel movie Marrying Mr. Darcy, a sequel to the popular film Unleashing Mr. Darcy. She has also been a recurring cast member on the Hallmark Channel series “Harmony” since 2021. In addition to her acting work, D’Orsay has been involved in various charitable causes, including the organization World Vision Canada, which provides assistance to children and communities in need around the world.

Brooke D’Orsay Now
Riki Lindhome – Then
In the show’s fifth season, Riki Lindhome played the role of Ramona Nowitzki, a graduate student who develops an obsessive crush on Dr. Sheldon Cooper after he gives a lecture at her university. Ramona is depicted as intelligent but socially awkward, and her behavior towards Sheldon becomes increasingly unsettling as she tries to get closer to him. Lindhome’s portrayal of Ramona was praised for its comedic timing and for adding an interesting twist to Sheldon’s character.

Riki Lindhome Then
Riki Lindhome – Now
In addition to her appearance on The Big Bang Theory, Lindhome has had notable roles in other television shows such as Gilmore Girls and The Muppets, and has co-created and starred in the comedy series Another Period. In addition to her acting work, she is also a musician and member of the comedy music duo Garfunkel and Oates, which she co-founded in 2007. The duo has released multiple albums and specials, and has also appeared in their own television series on IFC.

Riki Lindhome Now
Eliza Dushku – Then
Eliza Dushku is an American actress who made a brief guest appearance on the popular sitcom “The Big Bang Theory”. In the show’s fourth season, she played the role of an FBI agent named Angela Page who interviews Howard Wolowitz after he contacts the agency to report a security breach. Dushku’s character is portrayed as intelligent and tough, but also flirty and somewhat manipulative. Despite her brief appearance, Dushku brought a strong presence to the show and her performance as Angela Page was well-received by fans.

Eliza Dushku Then
Eliza Dushku – Now
Outside of her appearance on The Big Bang Theory, Dushku is perhaps best known for her roles in other television shows such as Buffy the Vampire Slayer and Dollhouse, as well as films like Bring It On and True Lies. In 2018, she had a recurring role on the CBS drama Bull, playing the character of J.P. Nunnelly. She has also been a producer on some of her recent projects, including the 2019 film Mapplethorpe and the 2020 documentary This Is Personal.

Eliza Dushku Now
Courtney Henggeler – Then
Courtney Henggeler is an American actress who made a guest appearance on the show’s seventh season. She played the role of Missy Cooper, the attractive but tough-talking fraternal twin sister of Sheldon Cooper. Missy is depicted as being the complete opposite of Sheldon in terms of personality, but the two share a close bond despite their differences. Henggeler’s performance as Missy was praised by fans for its humor and for adding an interesting dynamic to Sheldon’s backstory.

Courtney Henggeler Then
Courtney Henggeler – Now
Beyond her appearance on The Big Bang Theory, Henggeler is best known for her role as Amanda LaRusso in the hit Netflix series Cobra Kai. She has also had notable roles in other television shows such as Mom and The Ranch, as well as in films like The Bog Creatures and Nobody’s Perfect. In addition to her acting work, Henggeler is also an advocate for various causes. She has spoken out about her experience with postpartum depression and has encouraged other mothers to seek help if they are struggling. She has also been a supporter of organizations like St. Jude Children’s Research Hospital and the Trevor Project.

Courtney Henggeler Now
John Ross Bowie – Then
John Ross Bowie is an American actor who is best known for playing the character of Barry Kripke, a recurring character in the series who is a brilliant but socially awkward scientist at Caltech, where the main characters also work. Kripke is often portrayed as Sheldon Cooper’s rival, and the two frequently clash over scientific theories and experiments. Bowie’s performance as Kripke was praised for his ability to bring humor to the character’s quirks and idiosyncrasies.

John Ross Bowie Then
John Ross Bowie – Now
Beyond The Big Bang Theory, Bowie has had numerous other roles in both television and film. He has appeared in shows like Speechless, Veep, and CSI: Miami, and in films such as What the #$*! Do We (K)now!? and The Heat. In addition to his acting work, Bowie is also a writer and has contributed to the writing for various television shows, including The Big Bang Theory itself.

John Ross Bowie Now
Wil Wheaton – Then
Wil Wheaton is an American actor, writer, and producer who is perhaps best known for his recurring role on The Big Bang Theory. He played a fictionalized version of himself, who was portrayed as Sheldon Cooper’s arch-nemesis and the frequent winner of the comic book store’s “Mystic Warlords of Ka’a” tournament. Despite his antagonistic relationship with Sheldon, Wheaton’s character had several moments of redemption and showed a more vulnerable side in later seasons of the show.

Wil Wheaton Then
Wil Wheaton – Now
In addition to his appearances on The Big Bang Theory, Wheaton is also known for his roles in other popular television shows, such as Star Trek: The Next Generation, Eureka, and Teen Titans. He has also done extensive voice acting work for animated shows and video games, including the role of Aqualad in Young Justice. In addition to his acting work, Wheaton is also an accomplished writer and blogger. He has published several books, including a memoir titled “Just a Geek” and a collection of essays titled “Dancing Barefoot”. He is also a co-creator and host of the web series “Tabletop”, which features Wheaton and his friends playing various tabletop games.

Wil Wheaton Now